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Rejuvenis Polyzyme Enzymes

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          Why take enzymes?

The following is some of the information we offer to help make informed choices:

Probiotics & proteolytic enzyme easily survives stomach acid

The reason we're supposed to take probiotic supplements is to replace the probiotics that we used to get in a wide range of unprocessed fermented foods such as homemade yogurt, sauerkraut, buttermilk, pickled foods, kimchi, raw vinegar, tempeh, etc. -- foods that are no longer a significant part of our diet.

These foods are not enteric coated. How could these foods provide probiotic value if the beneficial bacteria were destroyed by stomach acid? The simple truth is that beneficial bacteria, for the most part, easily survive stomach acid. Also, if you take your probiotic supplements with water on an empty stomach they encounter almost no stomach acid and therefore remain effective.

Most people treat the symptom of stomach acid reflux with antacids and suppress stomach acid production, ultimately leading to long-term health problems.

The questions related to probiotics are essentially the same as those for proteolytic enzymes: aren't they broken down and destroyed by stomach acid -- thus requiring special, acid-proof capsules? And the answer, for most probiotics, is absolutely not. We believe this is primarily a marketing pitch for companies selling probiotics in enteric coated capsules, but the logic is flawed.

Enzyme absorption absolutely occurs and manifests through two main avenues:  Peristalsis & Pinocytosis.

Peristalsis not only forces food (and enzymes) down through the intestinal tract, it also forces transit through the intestinal wall.

Pinocytosis enzyme molecules are bound to, and encapsulated, by other substances such as water. Since they are encapsulated, the intestinal wall cannot recognize them as enzymes and thinks they are "water," thus readily passing them through the intestinal wall. Once the enzymes are in the bloodstream they attach to lymphocytes and travel easily throughout the vascular and lymphatic systems

Stomach acid and digestion

To start, you must first deal with these issues:

1. Too much stomach acid
2. Too little stomach acid
3. Stomach acid and proteolytic enzymes
4. Stomach acid and probiotics
5. Stomach acid and digestion

Before we can even talk about stomach acid, we need to spend a little time talking about how it fits in the digestive process. Most people believe that when you eat a meal it drops into a pool of stomach acid, where the food is then broken down and then goes into the small intestine to have nutrients taken out  and then into the colon to be passed out of the body, that is if you're lucky. Only this is not quite the case.

What nature intended is that you eat enzyme rich foods and chew your food properly. If you did that, the food would enter the stomach laced with digestive enzymes. These enzymes would then "predigest" your food for about an hour -- actually breaking down as much as 75% of your meal.

Only after this period of "pre-digestion" are hydrochloric acid and pepsin introduced. The acid inactivates all of the food-based enzymes, but begins its own function of breaking down what is left of the meal in combination with the acid energized enzyme pepsin. Eventually, this nutrient-rich food concentrate moves on into the small intestine. Once this concentrate enters the small intestine, the acid is neutralized and the pancreas reintroduces digestive enzymes to the process. As digestion is completed, nutrients are passed through the intestinal wall and into the bloodstream.

That's what nature intended. Unfortunately, most of us don't live our lives as nature intended!

Processing and cooking destroys enzymes in food.  Any sustained heat of approximately 180 F or above, destroys virtually all enzymes. This means that, for most of us, the food entering our stomach is severely enzyme deficient. The food then sits there for an hour, like a heavy lump, with very little pre-digestion taking place. This forces the body to produce large amounts of stomach acid in an attempt to overcompensate. In addition to failing in this attempt (much of the meal still enters the small intestine largely undigested), there are two major consequences.

1. Too much stomach acid;
2. Too little stomach acid; which still creates too much stomach acid

This is obvious. In an attempt to overcompensate for lack of enzymes in the food, the stomach produces an inordinate amount of stomach acid to compensate, leading to acid indigestion. Taking antacids or purple pills doesn't solve the problem; it merely masks one of the symptoms. Ultimately, though, it passes even more quantities of poorly digested food into the intestinal tract where it leads to intestinal putrefaction, gas, bloating, bad digestion, chronic digestive disorders, in addition to overworking your pancreas, which tries to compensate by producing huge amounts of digestive enzymes for use in the small intestine. All of this is exacerbated by foods and beverages such as alcohol (especially beer), high sugar foods, and caffeinated foods (coffee and tea, etc.) that can actually double acid production.

The simple solution for most people with excess stomach acid is to supplement with digestive enzymes which can digest up to 70% of the meal in the pre-acid phase, thus eliminating the need for large amounts of stomach acid and also taking tremendous stress off the digestive system and the pancreas.

One other factor which may be contributing to the problem is a hiatal hernia, in which part of the stomach can protrude through the diaphragm into the chest cavity allowing food and stomach acid to back up into the esophagus. Combine a hiatal hernia with excess stomach acid and you have the potential for great distress. The standard treatment for severe hiatal hernia is laparoscopic surgery -- with mixed results. Fortunately, there are chiropractic alternatives that can be quite effective.

In either case, dietary changes and supplemental digestive enzymes are likely to produce significant results, without creating problems further down the digestive tract.

Drinking 2-4 ounces of organic, stabilized, aloe vera juice every day can also help soothe irritated tissue in the esophagus and help balance out digestive juices in the stomach.

When you follow the logic, too little stomach acid will have similar symptoms as having too much.

If you spend years forcing your body to massively overproduce stomach acid to compensate for the lack of enzymes in your diet, what do you think the long-term consequences might be in terms of your ability to produce stomach acid?

The answer is: Eventually, your body's capacity to produce stomach acid begins to fade, along with a consistent loss in your body's ability to sufficiently process food in the stomach. The health consequences can be profound. Low production of stomach acid is quite common and becomes more prevalent with age due to our poor nutritional intake. This is the main reason why I say:  Chronological aging is inevitable however; biological aging is due to our poor choice in life. By age forty, 40% of the population is affected, and by age sixty, 50%. A person over age 40 who visits a doctor's office has about a 90% probability of having low stomach acid. Consequences can include:

Poor digestion. Not only is there insufficient stomach acid to break down food, there is insufficient acidity to optimize the digestive enzyme pepsin, which requires a pH of around 2.0. This results in partial digestion of food, leading to gas, bloating, belching, diarrhea/constipation, autoimmune disorders, skin diseases, rheumatoid arthritis, and a host of intestinal disorders such as Crohn's and irritable bowel syndrome (IBS). It is estimated that 80% of people with food allergies suffer from some degree of low acid production in the stomach.

Many vitamins and minerals require proper stomach acid in order to be properly absorbed, including: calcium, iron, vitamin B12, and folic acid. Vitamin B12 in particular requires sufficient stomach acid for proper utilization. Without that acid, severe B12 deficiency can result. (Note: ionic delivery systems can bypass this problem.)

With low acidity and the presence of undigested food, harmful bacteria are more likely to colonize the stomach and interfere with digestion. Normal levels of stomach acid help to keep the digestive system free of harmful bacteria and parasites.

It's worth noting that symptoms of low acidity include:

1. Bloating, belching, and flatulence immediately after meals.
2. Indigestion, diarrhea, or constipation.
3. Heartburn.  

This list sounds very similar to the symptoms associated with too much stomach acid? In fact, up to 95% of people who think they are suffering from too much stomach acid are actually suffering from the exact opposite condition. The use of antacids and purple pills then become exactly the wrong treatment to use since they exacerbate the underlying condition while temporarily masking the symptoms.


Supplementing with digestive enzymes to reduce the need for stomach acid -- giving the body a chance to rest and recover its ability to produce sufficient stomach acid. Mix one teaspoon of apple cider vinegar with water and a little honey and drink this with each meal. You might gradually increase the vinegar up to 3-4 tablespoons in water if needed.  Something I don’t advise my clients of, however does exist is; supplementing with betaine hydrochloride (HCL) tablets (which are a source of hydrochloric acid, a naturally occurring stomach acid that helps break up fats and proteins for further digestion in the small intestine) can possibly help, but anything beyond minimal doses as found in some health food store supplements should only be administered under the supervision of a health practitioner to avoid damage to the stomach lining.

Stomach acid and proteolytic enzymes

When we receive questions from our clients on this issue, most of them have nothing to do with high or low stomach acid, but rather with the effect of stomach acid on supplements. I remind them quickly that CO-Q-10 should always be taken in the form of a chewable tablet, so that the most value can be receive from the oral absorption from the inner lining of the mouth; however enzymes, probiotics and other vitamins far well in and through the stomach acid.

The great concern is with how stomach acid affects proteolytic enzymes, and pretty much ran along the following lines.

Since enzymes are made from proteins and proteolytic enzyme formulas are taken orally:

How do they survive the digestion of proteins that takes place in the stomach? Wouldn't they be broken down by stomach acid into amino acids?

If they do make it through the stomach, since they are so large, wouldn't they be unable to pass through the intestinal wall?

Surviving stomach acid!


Not all proteins and enzymes are proteins, are broken down by stomach acid. Not getting technical, I’ll point out pepsin. Pepsin is an enzyme secreted by the stomach to aid in digesting the proteins in your food. Not only is pepsin not broken down by stomach acid, pepsins optimum pH environment is about 2.0, which is very acidic.

But these facts show; that although some enzymes such as Serrapeptase are destroyed by stomach acid, most are not -- just temporarily rendered inactive.

(Note: that's one of the reasons I do not use Serrapeptase in my own proteolytic enzyme formulation.)
Different enzymes function differently in different pH environments, which is why I formulated my proteolytic enzyme formula, pHi-Zymes, to function in a wide range of pH's

The body produces metabolic enzymes in the pancreas and other organs but without the enzymes contained in each of Mother Nature’s foods, due to their being removed due to processing, we must supplement our body. We are born with the ability to make a finite amount of metabolic enzymes and through depletion due to the consumption of processed food plus what decreases with age, supplementation is vital. It is agreed that complete health is the sum total and soundness of our on individual enzyme system. Simply stated health and nutrition is:

1. The body’s ability to consume the 45 known nutrients in their proper amounts.

2. Digest these nutrients.

3. Absorb these nutrients.

4. Carry these nutrients into the cells.

5. Metabolize these nutrients.

6. Eliminate them as waste through the lymphatic system, adrenal cortex, liver, etc., without getting fat.

Since all 100 trillion cells in our bodies depend upon the reaction of metabolic enzymes and their energy factor it makes sense to use them solely for these tasks and not for digestion purposes.

When humans first evolved we ate everything raw and therefore no metabolic enzymes were required to assist digestion. Since all things in their raw form have the required amount of enzymes needed to cause digestion of that particular food, our metabolic enzyme production was left intact to support our metabolism.

In today’s world we eat processed foods and cook most everything we eat for sanitary purposes, even our vegetables. This destroys the enzymes in that particular food required for the digestion of that food. This causes our bodies to furnish our digestive systems with the use of our metabolic enzymes. Calorie Restricted and Appropriate Nutrition diets (CRAN) have been shown to extend life in animals. This is due to the fact that more often you eat during the day of healthy un-cooked fruits and vegetables and even though you eat less, what you eat over all is healthier in that diet and the less your demand is on your metabolic enzyme source for digestion.

One of the most important life extension portions of the Clinic’s program is supplementation for immune support and digestive enzymes and to limit inflammation; inflammation can limit joint function, and destroy bone, cartilage and other arteriole structures.  The prime cause of western diseases is now considered to be chronic inflammation caused by eating starchy carbohydrates, processed, micro-waved and generally overcooked foods. This is measured by the rise in C-Reactive proteins after eating such foods. When we have chronic inflammation as well as free radical damage, we get what is known as sticky blood, where the platelets stick together and can clot.

Digestive enzymes to decrease the body's dependencies on the metabolic enzyme supply are very important to supplement program we suggest after testing. Taken orally enzymes can have systemic absorption and systemic effects on the whole organism. If we postpone the debilitation of metabolic enzyme activity then we might delay the aging process. Disease is considered nothing more than the lack of or imbalance of enzymes.

Research findings for Serrapeptase!

The search for a superior enzyme that offers safe but powerful anti-inflammatory properties, thus averting the terrible side effects, ended when Serratia peptidase (Serrapeptase) enzyme was discovered in the early 70’s. Serrapeptase is now in wide clinical use throughout Europe and Asia as a viable alternative to salicylates, ibuprofen (sold as an OTC in the U.S.) and the more potent NSAIDs. Serrapeptase is an anti-inflammatory, proteolytic enzyme isolated from the microorganism, Serratia E15 and has no inhibitory effects on prostaglandins, is devoid of gastrointestinal side effects and offers a sensible alternative. Serrapeptase is processed commercially in the laboratory through fermentation. It was originally found in the silkworm where it is naturally present in its intestine. This immunologically active enzyme is completely bound to the alpha 2 macroglobulin in biological fluids. Histologic studies reveal powerful anti-inflammatory effects of this naturally occurring enzyme. The silkworm has a special relationship with the Serratia E15 microorganisms in its intestines. The enzymes secreted by the bacteria in silkworm intestines have the ability to dissolve avital tissue, but have no detrimental effect on the host’s living cells. Thus by dissolving the silkworm’s protective cocoon (avital tissue), the winged creature is able to emerge and fly away.

The discovery of this unique biological phenomenon led researchers to study clinical applications of the Serrapeptase enzyme in man. In addition to its widespread use in:


Fibrocystic breast disease

Carpal tunnel syndrome


Researchers in Germany have used Serrapeptase for atherosclerosis to digest atherosclerotic plaque without harming the healthy cells lining the arterial wall.

Atherosclerosis conditions as well as Cholesterol!

Today, researchers consider atherosclerosis an inflammatory condition (similar to many other degenerative diseases whose cause is identified as chronic inflammation). Some immunologists are even categorizing atherosclerosis as a benign tumour. Hardening and narrowing of the arterial wall is a cumulative result of microscopic trauma; inflammation occurs in the presence of oxidized lipids. Serrapeptase doesn’t interfere with the synthesis of cholesterol in the body, but acts as an anti-inflammatory and helps clear avital tissue from the arterial wall. It is important to note that cholesterol in its pure state is an antioxidant and a necessary component of the major organ and is at the top of hormonal pathway systems in the body. It is the most important hormone in the body. The use of medications, which block cholesterol biosynthesis, may eventually damage the liver and compromise anti-oxidant status of the eyes, lungs and other soft tissues as well as to disrupt the hormonal system.

Serrapeptase has been used as an anti-inflammatory agent in the treatment of:

Chronic sinusitis

To improve the elimination of bronchopulmonary secretions

Traumatic injury (e.g. sprains and torn ligaments)

Post-operative inflammation

To facilitate the therapeutic effect of antibiotics in the treatment of infections

Cystitis and epididymitis

Serrapeptase has been admitted as a standard treatment in Germany and other European countries for the treatment of inflammatory and traumatic swellings. Decreasing pain correlated for the most part with the reduction in swelling; also for improvement (due to inflammation) of breast pain, breast swelling and indurations, with persons receiving Serrapeptase who reported moderate to marked improvement. No adverse reactions were reported with the use of Serrapeptase. The use of enzymes with fibrinolytic, proteolytic and anti-edemic activities for the treatment of inflammatory conditions of the ear, nose and throat has gained increasing support in recent years.